We will open our clinic all days through Golden week.
Doctor’s schedule

Flow of Anti-VEGF Treatment

Flow of Anti-VEGF Treatment

1Your ophthalmologist will clean your eye to prevent infection. The eye is numbed to reduce pain.

2A small device may be placed on your eye to keep your eyelids out of the way.

3Your ophthalmologist injects the drug through the white part of your eye using a very thin needle.

4The injection only takes a few seconds. You usually do not see the needle itself.

5Your ophthalmologist will decide how many treatments you need. You may need other types of treatment along with anti-VEGF treatment.

Side Effects

Some of the side effects that have been noted in patients receiving this medication include inflammation of the eye and increased intraocular pressure, both of these seen in less than 1 percent of users who utilize anti-VEGF therapy. Patients will typically present with pain within 24 hours of injection but symptoms will generally resolve spontaneously.


In a study aimed at determining how effective anti-VEGF therapy for wet macular degeneration could actually be in a long-term study, participants were asked to continue therapy for 2 years and only come for therapy when new vessels were noted on eye examination. In this study, it was found that patients needed on average 8 visits during the first year but only 5 visits during the second year for anti-VEGF therapy. After 12 months and 24 months respectively, participants retain visual acuity of at least 15 letters in 97.5 and 95 percent of cases respectively.


Anti-VEGF therapy is covered by insurance; for one injection, approximately 40,000~50,000 yen. If you don’t have health insurance, it will cost about 140,000~160,000 yen for one injection.

Office hours






(no lunchtime.)


Our clinic is closed on 12/31, 1/1, 1/2, 1/3.


9th floor of Hulic Shinjuku Building,3-25-1, Shinjuku, Shinjuku-ku, Tokyo, 160-0022






Online appointment


Doctor career

Director:Yasuhiro Shinkawa

(Registered Recipient of a Diploma of Ophthalmology)


Japan Ophthalmological Society
Japanese Retina and Vitreous Society
Japanese Society of Ophthalmic Surgeons

Certification of Completion

Course of Ophthalmic PDT Study Group
Number of cataract surgery up to the present:About 4000


2001 Graduate-Medical Department of Kumamoto University
2002 Department of Ophthalmology Kyoto University School of medicine
2002 Shimada Municipal Hospital
2008 Japanese Red Cross Society
2010 Kitano Hospital The Tazuke Kofukai Medical Research Institute
2014 Shinjuku-Higashiguchi Eye Clinic


Doctor:Fumiyo Hasegawa

(Registered Recipient of a Diploma of Ophthalmology)


Japan Ophthalmological Society
Japan Ophthalmologists Associasion
Japanese Association for Strabismus and Amblyopia(JASA)


1992 Graduate- Medical Department of Teikyo Univercity
2002 The head ophthalmologist at International Catholic Hospital
2020 Shinjuku-Higashiguchi Eye Clinic

Main Thesis

Sequelae of ocular trauma in schools.(Japanese)
A case of periodic upper and lower strabismus with loss of periodicity after cataract surgery(Japanese)
Quantitative analysis of eye movement during a cover test for patients with intermittent exotropia(Japanese)

We have 7 full-time service orthoptist, 2 part-time orthoptists, 1 full-time nurse and 4 part-time nurses in our clinic.
Another several ophthalmologists are working here.